Antibody Response to Mannheimia Haemolytica Leukotoxin in Cattle with Respiratory Tract Disease
نویسندگان
چکیده
In order to obtain data concerning the involvement of Mannheimia haemolytica in bovine respiratory disease (BRD) outbreaks, a serological survey was carried out on paired (acuteconvalescent) sera from 1310 beef and 810 dairy cattle collected in 262 BRD outbreaks in Italian herds during 2002-2006. No vaccination program to M. haemolytica A1 was applied in the investigated herds. For each outbreak, 5 to 12 animals were considered for serum sampling. An enzyme linked immunosorbent assay (ELISA) was used to determine serum antibody response to M. haemolytica leukotoxin (LKT). Seroconversion involved 467 animals (22%), 314 beef cattle (24%) and 153 dairy cattle (19%), respectively. On a serological basis, M. haemolytica involvement was detected in 162 (62%) BRD outbreaks. Prevalence of seroconversion ranged from 20% to 60%. Concurrent seroconversion to M. haemolytica and the main bovine respiratory viruses was recorded in 141 (54%) outbreaks. Seroconversion to M. haemolytica LKT involved mainly cattle not vaccinated to BRD vi-
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